GS15081
Protein
Uniprot ID:P14719-2 (2-337aa)
Il1rl1, Ly84, St2, Ste2
Mammalian cell
Mus musculus (house mouse)
C-terminal FLAG-tagged;C-terminal His-tagged;
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-140℃.
For research use only
白細胞介素1受體樣1 (IL1RL1)是白細胞介素1受體家族的一員,包含3個ig樣c2型結構域和1個TIR結構域。它在腎、肺、胎盤、胃、骨骼肌、結腸和小腸中高度表達。IL1RL1是白細胞介素-33的受體,它的刺激招募MYD88, IRAK1, IRAK4和TRAF6,然后磷酸化MAPK3/ ERK1和/或MAPK1/ ERK2, MAPK14和MAPK8。IL1RL1可能參與輔助t細胞的功能??扇苄訧L1RL1還作為Th2細胞因子產(chǎn)生的負調(diào)節(jié)因子,它直接涉及心臟病的進展。