中文名稱: | 替加環(huán)素 |
中文別名: | (4S,4aS,5aR,12aS)-4,7-雙(二甲氨基)-9-[(叔丁基氨基)乙酰胺基]-3,10,12,12a-四羥基-1,11-二氧代-1,4,4a,5,5a,6,11,12a-八氫并四苯-2-甲酰胺 ; |
英文名稱: | Tigecycline |
英文別名: | Tigecyclin; 2-Naphthacenecarboxamide, 4,7-Bis(Dimethylamino)-9-[[[(1,1-Dimethylethyl)Amino]Acetyl]Amino]-1,4,4a,5,5a,6,11,12a-Octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4s,4as,5ar,12as)-; (4s,4as,5ar,12as)-4,7-bis(dimethylamino)-9-[(tert-butylamino)acetamido]-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracen-2-carboxamide; tigecycline glycylcycline ; (4S,4As,5ar,12as)-4,7-Bis(dimethylamino)-9-{(tert-butylamino)acetamido}-3,10,12,12a-octahydrotetracen-2-carboxamide; N-[(5aR,6aS,7S,9Z,10aS)-9-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-1,10a,12-trihydroxy-8,10,11-trioxo-5,5a,6,6a,7,8,9,10,10a,11-decahydrotetracen-2-yl]-N~2~-tert-butylglycinamide; (4S,4aS,5aR,12aS)-9-[(N-tert-butylglycyl)amino]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; Tigilcycline; Tigecycline hydrochloride |
CAS號(hào): | 220620-09-7 |
分子式: | C29H39N5O8 |
分子量: | 585.6487 |
用途:
替加環(huán)素由美國(guó)惠氏制藥公司開發(fā),2005年6月美國(guó)FDA批準(zhǔn)上市,劑型:凍干粉針,規(guī)格:50mg,用于治療18歲以上年齡患者由特定細(xì)菌的敏感菌株所致感染的治療