詳細(xì)介紹
產(chǎn)品名: ABT-199
Cas No.: 1257044-40-8
分子量: 868.44
分子式: C45H50ClN7O7S
別名: ABT199, ABT 199, GDC0199, GDC-0199
化學(xué)名:
4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
溶解性: >43.4mg/mL in DMSO
儲(chǔ)存條件: Store at -20°C
ABT-199是通過(guò)基于結(jié)構(gòu)的逆向過(guò)程而研發(fā)的,是一種新型的特異性BCL-2抑制劑,具有低濃度的親和力