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Recombinant Human IL-2 貨號:200-02 細胞因子

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Recombinant Human IL-2 貨號:200-02 細胞因子
細胞因子(cytokine,CK)是一類能在細胞間傳遞信息、具有免疫調(diào)節(jié)和效應(yīng)功能的蛋白質(zhì)或小分子多肽。
作用特點:多效性、重疊性、協(xié)同性、拮抗性和雙重性。

詳細介紹

Recombinant Human IL-2 貨號:200-02 細胞因子 

 

細胞因子受體的結(jié)構(gòu)和分類:根據(jù)細胞因子受體cDNA序列以及受體胞膜外區(qū)氨基酸序列的同源性和結(jié)構(gòu)征,可將細胞因子受體主要分為四種類型:免疫球蛋白超家族(IGSF)、造血細胞因子受體超家族、神經(jīng)生長因子受體超家族和趨化因子受體。

 

Catalog Number:
200-02
Synonyms:
T-cell growth factor (TCGF), Aldesleukin
Description:
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.
AA Sequence:
MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK AKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
 
 
 
 
Cross Reactivity:
Dog, Monkey, Mouse, Rat, Human, Bacteria, Leech, Cow, Human + Mouse, Cow + Mouse
Research Interests:
AIDS /  HIV AIDS / HIV Cancer Cancer
Cell Culture Cell Culture Diabetes /  Weight Regulation Diabetes / Weight Regulation
Immune System Immune System Inflammation Inflammation
Neurobiology Neurobiology Proliferation Proliferation
Stem Cells & Differentiation Stem Cells & Differentiation Wound Healing Wound Healing
Allergy Allergy Transplantation Transplantation
 
 
Country of Origin:
USA


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