行業(yè)產(chǎn)品

  • 行業(yè)產(chǎn)品

北京方程嘉鴻科技有限公司


當前位置：北京方程嘉鴻科技有限公司>>細胞因子>>Recombinant Human IGF-1 貨號:100-11 細胞因子

Recombinant Human IGF-1 貨號:100-11 細胞因子

返回列表頁
參  考  價面議
具體成交價以合同協(xié)議為準

產(chǎn)品型號

品       牌

廠商性質(zhì)生產(chǎn)商

所  在  地北京市

聯(lián)系方式：王杰查看聯(lián)系方式

更新時間：2016-01-16 07:04:25瀏覽次數(shù)：6243次

聯(lián)系我時，請告知來自 制藥網(wǎng)

產(chǎn)品簡介

Recombinant Human IGF-1 貨號:100-11 細胞因子
細胞因子(cytokine,CK)是一類能在細胞間傳遞信息、具有免疫調(diào)節(jié)和效應(yīng)功能的蛋白質(zhì)或小分子多肽。
作用特點：多效性、重疊性、協(xié)同性、拮抗性和雙重性。

詳細介紹

Recombinant Human IGF-1 貨號:100-11 細胞因子 

 

細胞因子受體的結(jié)構(gòu)和分類:根據(jù)細胞因子受體cDNA序列以及受體胞膜外區(qū)氨基酸序列的同源性和結(jié)構(gòu)征，可將細胞因子受體主要分為四種類型：免疫球蛋白超家族（IGSF）、造血細胞因子受體超家族、神經(jīng)生長因子受體超家族和趨化因子受體。

 

Catalog Number:
100-11
Synonyms:
Insulin-like Growth Factor-I, Somatamedin C, IGF-IA
Description:
The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor （IGF-IR）, but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds.
AA Sequence:
GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
 
 
 
 
Cross Reactivity:
Bacteria, Chicken, Cow, Frog, Horse, Monkey, Mouse, Pig, Rat, Sheep, Tiger Salamander, Hamster, Human, N/A
Research Interests:
Angiogenesis/ Cardiovascular Angiogenesis/ Cardiovascular Bone, Skeletal, Cartilage Bone, Skeletal, Cartilage
Diabetes / Weight Regulation Diabetes / Weight Regulation Inflammation Inflammation
Proliferation Proliferation Wound Healing Wound Healing
 
 
Country of Origin:
USA


您感興趣的產(chǎn)品PRODUCTS YOU ARE INTERESTED IN

制藥網(wǎng) 設(shè)計制作，未經(jīng)允許翻錄必究 .? ? ? Copyright(C)?2021 http://xingweiyishu.cn,All rights reserved.

以上信息由企業(yè)自行提供，信息內(nèi)容的真實性、準確性和合法性由相關(guān)企業(yè)負責，制藥網(wǎng)對此不承擔任何保證責任。 溫馨提示：為規(guī)避購買風險，建議您在購買產(chǎn)品前務(wù)必確認供應(yīng)商資質(zhì)及產(chǎn)品質(zhì)量。

會員登錄

×

請輸入賬號

請輸入密碼

=

請輸驗證碼

收藏該商鋪

請 登錄 后再收藏

提示

您的留言已提交成功！我們將在第一時間回復(fù)您~