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Protease Inhibitor Cocktail 返回列表頁

參考價:230

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型號
HY-K0010
品牌
MCE
廠商性質
代理商
所在地
杭州市

規(guī)格

1 mL 230元 10000支可售

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產地	進口	級別	其他
證書	ISO系列證書

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Protease Inhibitor Cocktail蛋白酶抑制劑

注：本產品僅用于科研，不可用于臨床

Description
& Advantages

Endogenous proteins are produced and removed in a balanced state, so their cellular levels are generally stable under stable environmental conditions. However, protein production is greatly halted and degradation is enhanced when cells are studied in vitro. To prevent the degradation of proteins under such conditions, one can utilize a cocktail of inhibitors of those enzymes known to be present.

Protease inhibitor cocktail is used in cell lysates or tissue extracts to increase protein stability. The cocktail functions to inhibit proteases that would degrade either phosphorylated or non-phosphorylated protein substrates.

Protease inhibitor cocktail has been optimized and tested for mammalian cell and tissue extracts. It contains inhibitors with a broad specificity for serine, cysteine, and acid proteases, and aminopeptidases. This cocktail is supplied as a ready-to-use solution in DMSO.

Publications

•Nature. 2023 Apr;616(7956):357-364. [Abstract]
•Nature. 2023 Mar 8. [Abstract]
•Nature. 2023 Mar;615(7951):349-357. [Abstract]
•Cell. 2019 Apr 4;177(2):370-383.e15. [Abstract]
•Science. 2021 Jul 30;373(6554):547-555. [Abstract]
•Cell Res. 2021 Mar;31(3):345-361. [Abstract]
•Immunity. 2023 Mar 14;56(3):620-634.e11. [Abstract]
•Cancer Cell. 2017 Nov 13;32(5):561-573.e6. [Abstract]
•Signal Transduct Target Ther. 2022 Dec 24;7(1):399. [Abstract]
•Signal Transduct Target Ther. 2021 Aug 9;6(1):299. [Abstract]
•Cell Discov. 2021 Jun 22;7(1):46. [Abstract]
•Cell Discov. 2020 Oct 20;6:72. [Abstract]
•Adv Mater. 2021 Dec;33(49):e2103471. [Abstract]
•Sci Immunol. 2022 Feb 4;7(68):eabk2092. [Abstract]
•Nat Cell Biol. 2022 Apr;24(4):471-482. [Abstract]
•Int J Oral Sci. 2023 Jan 16;15(1):7. [Abstract]

Price Comparison

蛋白酶抑制劑 Cocktail (EDTA-Free,100× in DMSO) Price Comparison Storage

The product should be stored at -20°C, and is stable for at least 12 months.

Protocol

Thaw at room temperature, add at 1:100 (v/v) dilution to solution samples (such as cell lysates or tissue extracts), before assaying.
Application Fields: Western Blot analysis, Co-IP, pull-down, IF, IHC, kinase assay and etc.

Components

Cat. No.	Product Name	Package
HY-K0010-1 mL	Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO)	1 mL
HY-K0010-10 mL	Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO)	1 mL × 10
HY-K0010-50 mL	Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO)	1 mL × 50
HY-K0010-100 mL	Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO)	1 mL × 100